eye off wash blood paint 24 hours enhanced manufacture One-step prep drape adhesion mucosal tissue saline challenge five-minute scrub persistent activity surgical conditions film-forming solution One-Step Patient Prep patient preoperative skin prep two-minute bactericidal efficacy other aqueous-based iodophor preps Povidone Iodine Non Adherent Dressing alcohol-based povidone iodine solution contained single-use sterile applicator